Within the United States, an emerging sector of healthcare innovation has been digital innovations that offer the ability to access to multiple and diverse populations, decrease operational expenses, and assist those in need from remote locations. Our chapter investigates digital therapeutics. Digital therapeutics are software-based interventions that treat diseases by positively changing individuals’ behaviours and closely tracking outcomes. We believe they have the potential to be one of these transformative innovations and are uniquely positioned to increase the quality of care while simultaneously decreasing the costs associated with it. We begin this chapter by examining the innovation environment surrounding digital therapeutics and discuss how it may benefit from the principles of responsible research and innovation (RRI). The RRI approach develops innovations with the impact on the stakeholders as the central consideration. We use this framework to analyze one company operating within this digital therapeutic arena, WellStart Health.